A group of three independent clinical trials called the POWER Trials Collaborative Research was conducted to examine the efficacy of various weight loss and weight management strategies.
These studies were conducted online and intended to be convenient and available to participants. They have experimented with various therapies, such as behavioral and lifestyle changes, medication, and surgery.
Grant UO1-HL087085 from the National Heart, Lung, and Blood Institute helped fund the POWER Trials Collaborative Research.
POWER Trials Collaborative Research Publications
National Heart Lung Blood Institute – POWER Trials Collaborative Research
2011
Glasgow RE, Gaglio B, Bennett G, Jerome GJ, Yeh HC, Sarwer DB, Appel L, Colditz G, Wadden TA, Wells B. (2011). Applying the PRECIS criteria to describe three effectiveness trials of weight loss in obese patients with comorbid conditions. Health Serv Res. Nov 2 doi: 10.1111/j.1475-6773.2011.01347.x
2010
Yeh, H.C., Clark, J.M., Emmons, K.M., Moore, R.H., Bennett, G.G., Warner, E.T., Sarwer, D.B., Jerome, G.J., Miller, 3rd E.R., Volger, S., Louis, T.A., Wells, B., Wadden, T.A., Colditz, G.A., Appel L.J. (2010). Independent but Coordinated Trials: Insights from the Practice Based Opportunities for Weight Reduction Trials Collaborative Research Group. Clinical Trials. 7(4):322-32.
2009
Wells, B. (2009). Weight Loss in Obese Adults with Cardiovascular Risk Factors: Three Randomized Control Trials to Assess Interventions in Clinical Practices. Obesity and Weight Management. 5(5): 207-209.
Be Fit, Be Well – POWER Trials Collaborative Research
Washington University, Harvard School of Public Health, and Kaiser Permanente Colorado
2012
Bennett, GG, Warner, ET, Glasgow, RE, Askew, S, Goldman, J, Ritzwoller, DP, Emmons, KM, Rosner, BA, Colditz, GA for the Be Fit, Be Well Study Investigators. (2012). Obesity Treatment for Socioeconomically Disadvantaged Patients in Primary Care Practice. Arch Intern Med. doi:10.1001/archinternmed.2012.1
2011
Glasgow RE, Gaglio B, Bennett G, Jerome GJ, Yeh HC, Sarwer DB, Appel L, Colditz G, Wadden TA, Wells B. Applying the PRECIS criteria to describe three effectiveness trials of weight loss in obese patients with comorbid conditions. Health Serv Res. 2011 Nov 2 doi: 10.1111/j.1475-6773.2011.01347.x
2010
Yeh, H.C., Clark, J.M., Emmons, K.M., Moore, R.H., Bennett, G.G., Warner, E.T., Sarwer, D.B., Jerome, G.J., Miller, 3rd E.R., Volger, S., Louis, T.A., Wells, B., Wadden, T.A., Colditz, G.A., Appel L.J. (2010). Independent but Coordinated Trials: Insights from the Practice Based Opportunities for Weight Reduction Trials Collaborative Research Group. Clinical Trials. 7(4):322-32.
2009
Greaney, ML, Quintiliani, LM, Warner,E.T., King,D.K., Emmons, K.M., Colditz, G.A., Glasgow, R.E., Bennett, G.G., (2009). Weight Management Among Patients at Community Health Centers: The “Be Fit, Be Well” Study. Obesity and Weight Management. 5(5): 222-228.
Last Updated: October 2011
This study was supported by the National Heart, Lung, and Blood Institute grant no. UO1-HL087071.
POWER Hopkins – POWER Trials Collaborative Research
Johns Hopkins University
2011
Appel, LJ., Clark, JM., Yeh, HC, Wang, NY, Coughlin, JW, Daumit, G, Miller, ER, Dalcin, A, Jerome, GJ, Geller, S, Noronha, G, Pozefsky, T, Charleston, Reynolds, JB, Durking, N, Rubin, RR, Louise, TA, Brancati, FL (2011). Comparative Effectiveness if Weight-Loss Interventions in Clinical Practice. New England Journal of Medicine. 365(20). doi: 10.1056/NEJMoa1108660
Glasgow RE, Gaglio B, Bennett G, Jerome GJ, Yeh HC, Sarwer DB, Appel L, Colditz G, Wadden TA, Wells B. (2011). Applying the PRECIS criteria to describe three effectiveness trials of weight loss in obese patients with comorbid conditions. Health Serv Res. doi: 10.1111/j.1475-6773.2011.01347.x
2010
Yeh, H.C., Clark, J.M., Emmons, K.M., Moore, R.H., Bennett, G.G., Warner, E.T., Sarwer, D.B., Jerome, G.J., Miller, 3rd E.R., Volger, S., Louis, T.A., Wells, B., Wadden, T.A., Colditz, G.A., Appel L.J. (2010). Independent but Coordinated Trials: Insights from the Practice Based Opportunities for Weight Reduction Trials Collaborative Research Group. Clinical Trials. 7(4):322-32.
2009
Jerome, G.J., Yeh, H.C., Dalcin, A., Reynolds, J., Gauvey-Kern, M.E., Charleston, J., Durkin, N., & Appel, L.J. (2009). Treatment of Obesity in Primary Care Practice: The Practice Based Opportunities for Weight Reduction (POWER) Trial at Johns Hopkins. Obesity and Weight Management. 5(5): 216-221.
Last Updated: 11/2011
This study was supported by the National Heart, Lung, and Blood Institute grant no. UO1-HL087085.
Healthways developed the website for both interventions in collaboration with Hopkins investigators and provided coaches for the call-center directed intervention.
Healthways also provided some research funding to supplement NIH support. Johns Hopkins University has an institutional consulting agreement with Healthways. Under this institutional agreement, the University is entitled to fees for consulting services.
Those faculty investigators who participate in the consulting services receive a portion of the University fees, either as research support or salary supplement as determined by their supervisors.
The terms of this arrangement are managed by the Johns Hopkins University in accordance with its conflict of interest policies.
POWER-UP – POWER Trials Collaborative Research
University of Pennsylvania
2011
Wadden TA, Volger, S, Sarwer, DB, Vetter, ML, Tsai, AG, Berkowitz, RI, Kumanyika, S, Schmitz, KH, Diewald, LK, Barg, R, Chittams, J, Moore, R (2011). A Two-Year Randomized Trial of Obesity Treatment in Primary Care Practice. New England Journal of Medicine. 365(20). doi:10.1056/NEJMoa1109220
Glasgow RE, Gaglio B, Bennett G, Jerome GJ, Yeh HC, Sarwer DB, Appel L, Colditz G, Wadden TA, Wells B. (2011). Applying the PRECIS criteria to describe three effectiveness trials of weight loss in obese patients with comorbid conditions. Health Serv Res. doi: 10.1111/j.1475-6773.2011.01347.x
Volger S, Vetter ML, Dougherty M, Panigrahi E, Egner R, Webb VL, Thomas JG, Sarwer DB, Wadden TA. (2011). Patients’ preferred terms for describing their excess weight: discussing obesity in clinical practice. Obesity. doi:10.1038/oby.2011.217
Vetter ML, Wadden TA, Lavenberg J, Moore RH, Volger S, Perez JL, Sarwer DB, Tsai AG. (2011). Relation of health-related quality of life to metabolic syndrome, obesity, depression and comorbid illnesses. Int J Obes, 35, 1087-1094.
2010
Yeh, H.C., Clark, J.M., Emmons, K.M., Moore, R.H., Bennett, G.G., Warner, E.T., Sarwer, D.B., Jerome, G.J., Miller, 3rd E.R., Volger, S., Louis, T.A., Wells, B., Wadden, T.A., Colditz, G.A., Appel L.J. (2010). Independent but Coordinated Trials: Insights from the Practice Based Opportunities for Weight Reduction Trials Collaborative Research Group. Clinical Trials. 7(4):322-32.
2009
Derbas J, Vetter M, Volger S, Khan Z, Panigrahi E, Tsai AG, Sarwer DB, Wadden TA. (2009). Improving weight management in primary care practice: a possible role for auxiliary health professionals collaborating with primary care physicians. Obesity and Weight Management. 2009;5: 210-215.
Last Updated: November 2011 This study was supported by the National Heart, Lung, and Blood Institute grant no. UO1-HL087072.
